Two brothers, one only two months old, died when fire gutted their two storey home in Fontenoy on Sunday.
Police said that three-year-old Jamal Frederick and his two-month-old brother, Javonte were asleep with their five-year-old brother, while their mother had gone to a nearby grocery shop.
The five-year-old, whose name was not disclosed, escaped unharmed.
Police said that the cause of the fire has not yet been determined.
So far this year, five people have died as a result of fires.
In March, three members of a family were also killed when fire gutted their home in the eastern parish of St Andrew.